Ethyl trifluoroacetate → HCID 86696495, compound

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Reaction Steps

To a stirred, 0° C., solution of N1-(2-(3-bromophenoxy)ethyl)ethane-1,2-diamine (4.7 g, 17.9 mmol) in anhydrous tetrahydrofuran (180 mL) was added ethyl trifluoroacetate [383-63-1] (2.1 mL, 17.9 mmol). The resultant solution was allowed to stir under N2 blanket for 15 minutes then evaporated to dryness to obtain N-{2-[2-(3-Bromo-phenoxy)-ethylamino]-ethyl}-2,2,2-trifluoro-acetamide as 6.3 g of yellow solid. LRMS (ESI) m/z 355.1/357.1 [(M+H)]+, calc'd for C12H14BrF3N2O2: 355.16.

Provenance & Evidence