Sodium Hydroxide → HCID 3337053, compound

Participants

Reaction Steps

KY-780-batch B KMnO4 (0.168 gr) was added to the cooled (ice water) solution of 2-hydroxy-2-(2-nitrophenyl)acetic acid (0.3 gr, 4.1 mmol), NaOH (70 mg) in water 6 ml. the mixture reaction was stirred for 2 h at 0° c. The mixture reaction was concentrated in vacuum and The residue was purified on C18-reversed phase flash chromatography column employing a linear gradient of 0-30% A in B (flow-rate 40 mL/min), where A is 0.1% formic acid in CH3CN and B is 0.1% of formic acid in water, yielding 80 mg (10%) of pure KY-780-batch B

Provenance & Evidence