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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 871083Generated: October 30, 2026

3-Fluorobenzylic alcohol → 6-bromo-5-fluoro-1-(3-fluorobenzyl)-1H-indole

https://huagongshe.com/reaction/871083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorobenzylic alcoholHCID 68008—
Reactant6-Bromo-1H-indole-3-carbonitrileHCID 11470067—
Reactant6-Bromo-5-fluoroindoleHCID 22262922—
Product6-bromo-5-fluoro-1-(3-fluorobenzyl)-1H-indoleHCID 90408774—

Reaction Steps

The title compound was prepared using the procedure described in Example 3A using 3-fluorobenzyl alcohol and 6-bromo-5-fluoro-1H-indole in place of benzyl alcohol and 6-bromo-1H-indole-3-carbonitrile, respectively. LCMS: 323.8 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969375B2
Source datasetuspto-grants-2015_03
ORD IDord-5bf9c962439341e2aab5259b830cdd92
Source noteuspto-grants-2015_03