HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzyl bromide → 6-bromo-5-fluoro-1-(3-fluorobenzyl)-1H-indole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzyl bromide | HCID 68007 | — |
| Reactant | 6-Bromo-5-fluoro-1H-indole-3-carbonitrile | HCID 53402957 | — |
| Product | 6-bromo-5-fluoro-1-(3-fluorobenzyl)-1H-indole-3-carbonitrile | HCID 90408436 | — |
Reaction Steps
The title compound was prepared as described in Example 28A using 6-bromo-5-fluoro-1H-indole-3-carbonitrile in place of 6-bromo-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile and using 1-(bromomethyl)-3-fluorobenzene in place of 4-(bromomethyl)tetrahydro-2H-pyran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969375B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-9bd0e3eaedbd42c7a663b029a6160550 |
| Source note | uspto-grants-2015_03 |