Isopropyl iodide → 9H-Fluorene, 9-(1-methylethyl)-

HRID 871192Notes

Reaction equation

HRID 871192 reaction equation
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16][CH2:17]C.IC(C)C.OC1O[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O>>[CH:16]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)([CH3:17])[CH3:15]

Participants

5

Reactant 4

HCID 6362Isopropyl iodideHCID 6853FluoreneHCID 10219674L-AltroseHCID 178418339Butyllithium

Product 1

HCID 186969H-Fluorene, 9-(1-methylethyl)-

Procedure

Fluorene (15.0 g, 90.4 mmol), n-BuLi (48.1 ml, 120 mmol, 2.5 M in hexane), RX=2-iodopropane (14.0 ml, 139.6 mmol). 42 was isolated as a yellowish solid (18.7 g, quant.). The analytical data were identical with these to be found in the literature (M. A. Schmidt, H. G. Alt, W. Milius, J. Organomet. Chem. 1996, 525, 15).

Workup

  1. custom42 was isolated as a yellowish solid (18.7 g, quant.)

Sources & evidence

ORD record
ord-1e83d68f28a54b908502277d24e24173
Source dataset
uspto-grants-2015_03
Patent number
US08969624B2

Reaction notes

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