Hydrochloric Acid → HCID 70926185, compound

Participants

Reaction Steps

0.51 g (0.95 mmol) of the product prepared in step 4.4 is suspended in 10 mL of a dichloromethane/methanol mixture (v/v=8/2), and 3.55 mL (14.20 mmol) of a 4N solution of hydrogen chloride in dioxane are added. The mixture is stirred at room temperature overnight, and ether is added. The solid is drained by suction, rinsed with pentane and dried in an oven. 0.48 g the expected product is obtained in the form of a beige-coloured solid, which is used as obtained in the following step. Yield (dihydrochloride)=99.1°A. m.p.=117°C. M+H+=408.

Provenance & Evidence