Pyridine → HCID 67325480, compound

Participants

Reaction Steps

To a solution of 2.0 g (13.14 mmol) of N-methyl-4-nitroaniline (Aldrich) and 1.59 mL (19.72 mmol) of pyridine in 15 mL of tetrahydrofuran are added slowly 1.43 mL (15.77 mmol) of cyclopropanoyl chloride. The mixture is refluxed for 2 hours and evaporated to dryness. The residue is taken up in an ethyl acetate/water mixture and the organic phase is then dried over Na2SO4, filtered and concentrated under vacuum. The expected product is obtained in the form of a yellow oil, which is used as obtained in the following step.

Provenance & Evidence