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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 872207Generated: October 27, 2026

4-Nitrophenyl chloroformate → Carbonic acid 4-nitro-phenyl ester (R)-2,2,2-trifluoro-1-methyl-ethyl ester

https://huagongshe.com/reaction/872207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrophenyl chloroformateHCID 82129—
Reactant(2R)-1,1,1-trifluoropropan-2-olHCID 6993809—
ProductCarbonic acid 4-nitro-phenyl ester (R)-2,2,2-trifluoro-1-methyl-ethyl esterHCID 86704996—

Reaction Steps

The title compound is prepared from (R)-1,1,1-trifluoro-propan-2-ol and 4-nitrophenyl chloroformate following a procedure analogous to that described for Intermediate 20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975277B2
Source datasetuspto-grants-2015_03
ORD IDord-8a68436fe7734afe877ec85d69e0b620
Source noteuspto-grants-2015_03