4-Nitrophenyl chloroformate → Carbonic acid 4-nitro-phenyl ester (R)-2,2,2-trifluoro-1-methyl-ethyl ester

HRID 872207노트

반응식

HRID 872207 반응식
[F:1][C:2]([F:7])([F:6])[C@H:3]([OH:5])[CH3:4].Cl[C:9]([O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1)=[O:10]>>[F:1][C:2]([F:7])([F:6])[C@H:3]([O:5][C:9](=[O:10])[O:11][C:12]1[CH:13]=[CH:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=1)[CH3:4]

참가 물질

3

반응물 2

HCID 821294-Nitrophenyl chloroformateHCID 6993809(2R)-1,1,1-trifluoropropan-2-ol

생성물 1

HCID 86704996Carbonic acid 4-nitro-phenyl ester (R)-2,2,2-trifluoro-1-methyl-ethyl ester

실험 절차

The title compound is prepared from (R)-1,1,1-trifluoro-propan-2-ol and 4-nitrophenyl chloroformate following a procedure analogous to that described for Intermediate 20.

출처 및 근거

ORD 기록
ord-8a68436fe7734afe877ec85d69e0b620
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08975277B2

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