Methylamine → HCID 66665891, compound

Participants

Reaction Steps

A mixture of 2-[4-(1-tert-butoxycarbonylamino-cyclobutyl)-phenyl]-3-phenyl-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester (100 mg) and a solution of methylamine in methanol (2M, 1.4 mL) was heated at 100° C. under microwave irradiation for 90 minutes followed by a further 90 minutes. On cooling, the reaction mixture was concentrated in vacuo to give the title compound which was used without further purification in the next step.

Provenance & Evidence