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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 872318Generated: October 30, 2026

2-Methoxyethylamine → HCID 66664959, compound

https://huagongshe.com/reaction/872318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
ReactantHCID 66665523HCID 66665523—
SolventTetrahydrofuranHCID 8028—
ProductHCID 66664959HCID 66664959—

Reaction Conditions

Temperature110 °C

Reaction Steps

A mixture of {1-[4-(6-chloromethyl-3-phenyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester (103 mg) and 2-methoxyethylamine (31 mg, 0.035 mL) in THF (1.1 mL) was heated at 110° C. under microwave irradiation for 1 hour. On cooling, the reaction mixture was concentrated in vacuo to give the crude title compound which was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975265B2
Source datasetuspto-grants-2015_03
ORD IDord-5a30eb41a4b140379e1d56eef709e53d
Source noteuspto-grants-2015_03