Ammonia → HCID 56644404, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-[4-(1-amino-cyclobutyl)-phenyl]-3-phenyl-imidazo[1,2-a]pyridine-8-carboxylic acid methyl ester (Example 2-23, 128 mg) and ammonia (2.23 mL of a 7M aqueous solution) was heated at 130° C. under microwave irradiation for 90 minutes. On cooling, the reaction mixture was concentrated to give the title compound.

Provenance & Evidence