Hydrochloric Acid → 1-{4-[6-(2-Benzyloxy-pyridin-3-yl)-3-phenyl-imidazo[1,2-a]pyridin-2-yl]-phenyl}-cyclobutylamine

Participants

Reaction Conditions

Reaction Steps

The crude product from Step 2 (240 mg) was dissolved in DCM/MeOH (1.2 mL/0.76 mL), cooled to 0° C. and treated with HCl (4 M soln in dioxane, 0.94 mL). The reaction was warmed to rt and stirred for 2 hours. The reaction was poured onto ice and extracted with DCM (3×). The organic phase was washed with brine, dried and concentrated in vacuo to give the crude title compound.

Provenance & Evidence