1-{4-[6-(2-Benzyloxy-pyridin-3-yl)-3-phenyl-imidazo[1,2-a]pyridin-2-yl]-phenyl}-cyclobutylamine → HCID 178507126, compound

Participants

Reaction Steps

The crude product from Step 3 (167 mg) was dissolved in EtOH (7 mL) whereupon a precipitate formed which was filtered. The filtrate was hydrogenated using an H-Cube flow reactor (Pd/C cartridge, oven temperature 50° C.). The eluant was collected from the flow reactor in two fractions. The second fraction was concentrated in vacuo and triturated with DCM to give a solid which was filtered and dried to give a further portion of title compound (16 mg).

Provenance & Evidence