Acetic Acid → HCID 178509297, compound

HRID 872368Notes

Reaction equation

HRID 872368 reaction equation
C(O)(=O)C.OO.[NH2:7][C:8]1[N:12]=[C:11]([SH:13])[NH:10][N:9]=1.[OH-].[Na+]>O>[NH2:7][C:8]1[N:12]=[C:11]([S:13][S:13][C:11]2[NH:10][N:9]=[C:8]([NH2:7])[N:12]=2)[NH:10][N:9]=1

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1785092965-amino-1H-1,2,4-triazole-3-thiol

Product 1

HCID 178509297HCID 178509297, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Glacial acetic acid (2.60 g) was added to 4.89 g of a 15% aqueous hydrogen peroxide solution. The resulting solution was added over 20 minutes to a solution prepared from 5.01 g 3-amino-1,2,4-triazole-5-thiol, 65.2 g of water and 4.33 g 40% NaOH. The reaction mixture was kept between 18 C-22 C by use of an ice bath during the addition. After stirring for 75 min, the product was filtered, washed with water and then dried under vacuum at 70 C.

Workup

  1. additionThe resulting solution was added over 20 minutes to a solution
  2. additionThe reaction mixture was kept between 18 C-22 C by use of an ice bath during the addition
  3. filtrationthe product was filtered
  4. washwashed with water
  5. customdried under vacuum at 70 C

Sources & evidence

ORD record
ord-d16a65306b77458785f7cbfc99920831
Source dataset
uspto-grants-2015_03
Patent number
US08975316B2

Reaction notes

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