HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 67170271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl 2-chloro-2-(hydroxyimino)acetate | HCID 6399471 | — |
| Reactant | 2H-Pyran, tetrahydro-2-[(1-methyl-3-butynyl)oxy]- | HCID 10899081 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 67170271 | HCID 67170271 | — |
Reaction Steps
Ethyl chlorooximidoacetate (1 g, 6.60 mmol) and 2-(pent-4-yn-2-yloxy)tetrahydro-2H-pyran (3.33 g, 19.80 mmol) were dissolved in diethyl ether (20 ml) and the mixture was stirred vigorously. Triethylamine (0.920 ml, 6.60 mmol) diluted with diethyl ether was added dropwise. The reaction mixture was extracted with water and the organic phase dried with MgSO4, filtered and evaporated. The product was used in the next step without further purifications. LC-MS: [M+1]=284.32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975254B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-39fca2328ee941cb9b5c7b3a0bcfedc8 |
| Source note | uspto-grants-2015_03 |