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HRID872911

反应详情

EQUATION

反应方程式

HRID 872911 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCn2cc(C(=O)O)nc2C1
HCID44558548

7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid

C12H17N3O4

结构：C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1
HCID67170882

4-[1-[(2S)-2-Aminopropyl]-1H-pyrazol-3-yl]-2-chlorobenzonitrile

C13H13ClN4

PRODUCTS

生成物

1
结构：C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn2c(n1)CN(C(=O)OC(C)(C)C)CC2
HCID70654136

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using the method of Example 34(d) starting from 7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid (0.044 g, 0.165 mmol) and (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile (0.033 g, 0.127 mmol). The product was purified by flash chromatography. LC-MS: [M+1]=510.988.

WORKUP

后处理

  1. customThe product was purified by flash chromatography