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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 872911Generated: October 30, 2026

7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid → HCID 70654136, compound

https://huagongshe.com/reaction/872911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acidHCID 44558548—
Reactant(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrileHCID 67170882—
ProductHCID 70654136HCID 70654136—

Reaction Steps

The title compound was prepared using the method of Example 34(d) starting from 7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid (0.044 g, 0.165 mmol) and (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile (0.033 g, 0.127 mmol). The product was purified by flash chromatography. LC-MS: [M+1]=510.988.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975254B2
Source datasetuspto-grants-2015_03
ORD IDord-1ed57c97c31d494eb1bd91ad827e33a3
Source noteuspto-grants-2015_03