HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → HCID 86724162, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 135743575 | HCID 135743575 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86724162 | HCID 86724162 | 53.5% |
Reaction Steps
A mixture of 7-chloro-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one (700 mg, 4.08 mol), 2-iodopropane (1.04 g, 6.12 mmol) and Cs2CO3 (2.66 g, 8.16 mmol) in acetonitrile (15 mL) was refluxed for 3 h, filtered and concentrated to remove solvent to get crude product (700 mg) without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-eefb52ef16654f9bbc878df88682ece4 |
| Source note | uspto-grants-2015_03 |