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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873114Generated: October 26, 2026

3,4-Difluorobenzaldehyde → 2-Fluoro-5-(2-fluoro-4-formylphenoxy)benzonitrile

https://huagongshe.com/reaction/873114

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DifluorobenzaldehydeHCID 588088—
Reactant2-Fluoro-5-hydroxybenzonitrileHCID 22612410—
Product2-Fluoro-5-(2-fluoro-4-formylphenoxy)benzonitrileHCID 86724181—

Reaction Steps

The title compound was prepared by a procedure similar to that described for D4 starting from 3,4-difluorobenzaldehyde (188 mg, 1.32 mmol) and 2-fluoro-5-hydroxybenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-aa11a3eb89f34b9f8d33a2fa07c214d7
Source noteuspto-grants-2015_03