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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873175Generated: October 25, 2026

(4-(3,4-Difluorophenoxy)-3-fluorophenyl)methanol → 7-((4-(3,4-difluorophenoxy)-3-fluorobenzyl)oxy)-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/873175

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-(3,4-Difluorophenoxy)-3-fluorophenyl)methanolHCID 43554868—
Reactant7-Chloro-1-methyl-2,3-dihydroimidazo[1,2-C]pyrimidin-5(1H)-oneHCID 71743458—
Product7-((4-(3,4-difluorophenoxy)-3-fluorobenzyl)oxy)-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 71240923—

Reaction Steps

The title compound was prepared by a procedure similar to those described for E1 starting from 7-chloro-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (4-(3,4-difluorophenoxy)-3-fluorophenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-d7bd313f9bb64a4dafa5f8fd88941af2
Source noteuspto-grants-2015_03