HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 71243755, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3,4-Difluorobenzyl alcohol | HCID 522833 | — |
| Reactant | Tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-C]pyrimidine-1(5H)-carboxylate | HCID 71743561 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 71243755 | HCID 71243755 | — |
Reaction Steps
Prepared in a manner similar to that described for E65 using sodium hydride (44.2 mg, 1.104 mmol) in THF (5 mL), (3,4-difluorophenyl)methanol (106 mg, 0.736 mmol) and tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate (100 mg, 0.368 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-4a50c04bd393466ea1ebd4f6dc277f2b |
| Source note | uspto-grants-2015_03 |