HCID 71240935, compound → HCID 71243828, compound

HRID 873198Notes

Reaction equation

HRID 873198 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:35]=[CH:36][C:37]=1[F:38])[O:5][C:6]1[CH:30]=[CH:29][C:9]([CH2:10][O:11][C:12]2[CH:13]=[C:14]3[N:21](C(OC(C)(C)C)=O)[CH2:20][CH2:19][N:15]3[C:16](=[O:18])[N:17]=2)=[CH:8][C:7]=1[C:31]([F:34])([F:33])[F:32]>CN(C=O)C>[F:1][C:2]1[CH:3]=[C:4]([CH:35]=[CH:36][C:37]=1[F:38])[O:5][C:6]1[CH:30]=[CH:29][C:9]([CH2:10][O:11][C:12]2[CH:13]=[C:14]3[NH:21][CH2:20][CH2:19][N:15]3[C:16](=[O:18])[N:17]=2)=[CH:8][C:7]=1[C:31]([F:33])([F:34])[F:32]

Participants

3

Reactant 1

HCID 71240935HCID 71240935, compound

Product 1

HCID 71243828HCID 71243828, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared in a manner similar to that described for E71 using tert-butyl 7-((4-(3,4-difluorophenoxy)-3-(trifluoromethyl)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylat in DMF (2 mL) and silica gel.

Workup

  1. customPrepared in a manner similar to

Sources & evidence

ORD record
ord-35cbc8644307423d96bbf97b31a1d095
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

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