HCID 71243717, compound → HCID 86724205, compound

HRID 873206Notes

Reaction equation

HRID 873206 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:25]=[CH:26][C:27]=1[O:28][C:29]1[CH:34]=[CH:33][N:32]=[C:31]([C:35]([F:38])([F:37])[F:36])[CH:30]=1)[CH2:6][O:7][C:8]1[CH:9]=[C:10]2[N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15][N:11]2[C:12](=[O:14])[N:13]=1)#[N:2]>CN(C=O)C>[O:14]=[C:12]1[N:11]2[CH2:15][CH2:16][NH:17][C:10]2=[CH:9][C:8]([O:7][CH2:6][C:5]2[CH:25]=[CH:26][C:27]([O:28][C:29]3[CH:34]=[CH:33][N:32]=[C:31]([C:35]([F:37])([F:38])[F:36])[CH:30]=3)=[C:3]([CH:4]=2)[C:1]#[N:2])=[N:13]1

Participants

3

Reactant 1

HCID 71243717HCID 71243717, compound

Product 1

HCID 86724205HCID 86724205, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared in a manner similar to that described for E71 tert-butyl 7-((3-cyano-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimi-dine-1(5H)-carboxylate (80 mg, 0.151 mmol) in DMF (2 mL) and silica gel.

Workup

  1. customPrepared in a manner similar to

Sources & evidence

ORD record
ord-139d066e2882450eaacfb1fb1413c11c
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

Loading…