HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 7-((4-(3,4-dichlorophenoxy)-3-fluorobenzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate → 7-((4-(3,4-dichlorophenoxy)-3-fluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimi-din-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 7-((4-(3,4-dichlorophenoxy)-3-fluorobenzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 71243763 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 7-((4-(3,4-dichlorophenoxy)-3-fluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimi-din-5(1H)-one | HCID 86724208 | — |
Reaction Steps
Prepared in a manner similar to that described for E71 using tert-butyl 7-((4-(3,4-dichlorophenoxy)-3-fluorobenzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate (30 mg, 0.057 mmol) in DMF (2 mL) and silica gel (150 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-ad2917a9c90c4734ba7b49d1a8ad88cc |
| Source note | uspto-grants-2015_03 |