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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873223Generated: November 3, 2026

Trifluoroacetic acid → HCID 71243830, compound

https://huagongshe.com/reaction/873223

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 71241024HCID 71241024—
SolventDichloromethaneHCID 6344—
ProductHCID 71243830HCID 71243830—

Reaction Steps

Prepared in a manner similar to that described for E60 using tert-butyl 7-((3-cyano-4-((5,6-difluoropyridin-3-yl)oxy)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate (14 mg, 0.028 mmol) in DCM (4 mL) and TFA (0.5 mL, 6.49 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-0fbec35efed440228d1f398a30297eef
Source noteuspto-grants-2015_03