HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 7-((3-fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-5-oxo-2,3 dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate → 7-((3-fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 7-((3-fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-5-oxo-2,3 dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 71243818 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 7-((3-fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one | HCID 71241026 | — |
Reaction Steps
Prepared in a manner similar to that described for E71 using tert-butyl 7-((3-fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyri-midine-1(5H)-carboxylate (50 mg, 0.096 mmol) in DMF (2 mL) and silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-63f36dbdfb574973bba882484233a42b |
| Source note | uspto-grants-2015_03 |