HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 71241157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 71241010 | HCID 71241010 | — |
| Reactant | 7-Chloro-1-methyl-2,3-dihydroimidazo[1,2-C]pyrimidin-5(1H)-one | HCID 71743458 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 71241157 | HCID 71241157 | — |
Reaction Steps
Prepared in a manner similar to that described for E1 using 2-chloro-4-(2-fluoro-4-(hydroxymethyl)phenoxy)benzonitrile (100 mg, 0.360 mmol) in THF (8 mL), sodium hydride (21.6 mg, 0.540 mmol) and 7-chloro-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one (66.8 mg, 0.360 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-0d3deb7d9cc64566ac8d5840c3aba94a |
| Source note | uspto-grants-2015_03 |