HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 71241052, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 7-Chloro-1-methyl-2,3-dihydroimidazo[1,2-C]pyrimidin-5(1H)-one | HCID 71743458 | — |
| Reactant | HCID 86724221 | HCID 86724221 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 71241052 | HCID 71241052 | — |
Reaction Steps
Prepared in a manner similar to that described for E1 using 4-(2,6-difluoro-4-(hydroxymethyl)phenoxy)-2-(trifluoromethyl)benzonitrile (280 mg, 0.850 mmol) in DMF (5 mL), sodium hydride (61.2 mg, 2.55 mmol) and 7-chloro-1-methyl-2,3-dih-ydroimidazo[1,2-c]pyrimidin-5(1H)-one (158 mg, 0.850 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-a22cb19d64ce43bab58209d925d5be9b |
| Source note | uspto-grants-2015_03 |