Methyl iodide → HCID 46847804, compound

HRID 873249Notes

Reaction equation

HRID 873249 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:18](=[O:19])[C:17]3[C:12](=[CH:13][CH:14]=[N:15][C:16]=3[NH:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[NH:11][CH:10]=2)=[CH:5][CH:4]=1.IC.I[CH2:30][CH3:31]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[C:18](=[O:19])[C:17]3[C:12](=[CH:13][CH:14]=[N:15][C:16]=3[NH:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[N:11]([CH2:30][CH3:31])[CH:10]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 6340IodoethaneHCID 46847433HCID 46847433, compound

Product 1

HCID 46847804HCID 46847804, compound

Procedure

The title compound was prepared as described in Example 2 above except that 3-(4-chlorophenyl)-1,4-dihydro-4-oxo-5-(2-phenethylamino)-1,6-naphthyridine was replaced with 3-(4-methoxyphenyl)-1,4-dihydro-4-oxo-5-phenylamino-1,6-naphthyridine and iodomethane was replaced with iodoethane. MS 372 (M+1)+.

Sources & evidence

ORD record
ord-bc708168dc1e42c4b22d5b10115db031
Source dataset
uspto-grants-2015_03
Patent number
US08975407B2

Reaction notes

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