反应详情

A 10% palladium carbon catalyst (wet) (3.15 g) was added to a solution of the methyl 3-(benzyloxy)-6-[4-methoxy-2-methyl-3-(3,3,6,6-tetramethyl-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)phenyl]pyridine-2-carboxylate produced in Example 11-2 (3.15 g, 4.95 mmol) in THF (63 ml) at room temperature, and the mixture thus obtained was then stirred under a hydrogen atmosphere at room temperature for 3 hours. A solid was removed from the reaction solution by filtration, and the solvent was then distilled away from the filtrate thus obtained under reduced pressure to obtain the title compound (2.58 g, yield: 95%).

1. customthe mixture thus obtained
2. customA solid was removed from the reaction solution by filtration
3. distillationthe solvent was then distilled away from the filtrate
4. customthus obtained under reduced pressure