Methylhydrazine → HCID 86702121, compound

HRID 873606Notes

Reaction equation

HRID 873606 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=O)[CH2:11][C:12](=O)[C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:20][NH:21][NH2:22]>FC(F)(F)C(O)C(F)(F)F>[CH3:20][N:21]1[C:10]([C:7]2[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)=[CH:11][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[N:22]1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 605909HCID 605909, compound

Product 1

HCID 86702121HCID 86702121, compound

Reagents, catalysts & solvents 1

HCID 135291,1,1,3,3,3-Hexafluoro-2-propanolSolvent

Procedure

Ethyl 4-(4-nitrophenyl)-2,4-dioxobutanoate (500 mg, 1.885 mmol) was dissolved in hexafluoroisopropanol (4 ml) and methylhydrazine (87 mg, 1.885 mmol) was added dropwise. The reaction mixture was stirred at room temperature for 3 hours, concentrated to dryness, triturated with ether; and filtered to provide the title compound.

Workup

  1. concentrationconcentrated to dryness
  2. customtriturated with ether
  3. filtrationand filtered

Sources & evidence

ORD record
ord-287f40f523cf4d39baddbff4b5db4974
Source dataset
uspto-grants-2015_03
Patent number
US08975398B2

Reaction notes

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