2-Aminopyrimidine → HCID 86691079, compound

Participants

Reaction Conditions

Reaction Steps

2-Bromo-1-pyridin-2-ylethanone (66.1 g; 330 mmol) was dissolved in ethanol (330 mL), 2-aminopyrimidine (31.5 g; 330 mmol) was added thereto, and the mixture was stirred for 17 hours at 70° C. The precipitated crystals were collected by filtration, washed with acetone, and then dried to give 70.7 g of the title compound (yield 77%).

Provenance & Evidence