HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-fluoro-1-methyl-5-nitropyridin-2(1H)-one → 5-amino-3-fluoro-1-methylpyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-fluoro-1-methyl-5-nitropyridin-2(1H)-one | HCID 117702979 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 5-amino-3-fluoro-1-methylpyridin-2(1H)-one | HCID 117702611 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described in Step 5.2 using 3-fluoro-1-methyl-5-nitropyridin-2(1H)-one (Step 14.1). tR: 0.22 min (LC-MS 2); ESI-MS: 143 [M+H]+ (LC-MS 2); Rf=0.25 (CH2Cl2/MeOH 9:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975417B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-0e865c11690b4b6ab444a75c2118c079 |
| Source note | uspto-grants-2015_03 |