HCID 117702949, compound → HCID 117702711, compound

HRID 873831Notes

Reaction equation

HRID 873831 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:19][CH2:20][C:21]2[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=2)[C:9]2[C:10]([C:16](O)=[O:17])=[N:11][N:12]([CH3:15])[C:13]=2[CH3:14])=[CH:4][CH:3]=1>CCOC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[C:9]3[C:10](=[N:11][N:12]([CH3:15])[C:13]=3[CH3:14])[C:16](=[O:17])[N:19]2[CH2:20][C:21]2[CH:22]=[CH:23][C:24]([O:27][CH3:28])=[CH:25][CH:26]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 117702949HCID 117702949, compound

Product 1

HCID 117702711HCID 117702711, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared in analogy to the procedure described in Example 1 using 4-((4-chlorophenyl)((4-methoxybenzyl)amino)methyl)-1,5-dimethyl-1H-pyrazole-3-carboxylic acid (Step 25.4). tR: 5.07 min (HPLC 1); tR: 1.11 min (LC-MS 2); ESI-MS: 382.2 [M+H]+ (LC-MS 2); Rf=0.46 (EtOAc).

Sources & evidence

ORD record
ord-68a882bce4fe4156a3c2b1a5940bf495
Source dataset
uspto-grants-2015_03
Patent number
US08975417B2

Reaction notes

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