HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzaldehyde → ethyl 4-((4-chlorophenyl)(hydroxy)methyl)-1-cyclopropyl-3-(trifluoromethyl)-1H-Pyrazole-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | ethyl 1-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylate | HCID 117702900 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | ethyl 4-((4-chlorophenyl)(hydroxy)methyl)-1-cyclopropyl-3-(trifluoromethyl)-1H-Pyrazole-5-carboxylate | HCID 117702683 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described in Step 40.2 using ethyl 1-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylate (Step 44.1) and 4-chlorobenzaldehyde. tR: 1.29 min (LC-MS 2); ESI-MS: 389 [M+H]+ (LC-MS 2); Rf=0.12 (hexane/15% EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975417B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-fb005f8ea2ca466cb018d10349654917 |
| Source note | uspto-grants-2015_03 |