Methyl iodide → HCID 178481311, compound

Participants

Reaction Conditions

Reaction Steps

Methyl iodide (0.13 ml; 2 mmol) is added to a solution of 1-phenyl-1,2,4-triazole—which was obtained according to Antilla, J. C. et al., Journal of Organic Chemistry 2004, 69, 5578-5587—(0.15 g; 1 mmol) in 1 ml of acetonitrile. This mixture is heated at 80° C. for 16 hours, and is then evaporated to dryness. The residue obtained is recrystallized from a minimum amount of ethyl acetate, thus making it possible to obtain 0.12 g of the desired product (41%) whose characteristics are the following:

Provenance & Evidence