Benzyl Bromide → HCID 86655187, compound

HRID 874172Notes

Reaction equation

HRID 874172 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH3:18])[C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:19]([Br:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>C1(C)C=CC=CC=1>[Br-:26].[CH2:19]([N:8]1[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:11]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[N+:10]([CH3:18])=[CH:9]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 129747981-Methyl-4,5-diphenyl-1H-imidazole

Product 1

HCID 86655187HCID 86655187, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In a 25 ml one-necked flask, there is dissolved 0.240 g (1.024 mmol) of 4,5-diphenyl-1-methylimidazole, which was obtained according to Zeitschrift fuer Naturforschung, B: Chemical Sciences (2003), 58(4), 305-310, in 10 ml of toluene and then 183 μl (1.536 mmol) of benzyl bromide are added. After 2 days of heating under reflux, the reaction medium is concentrated under reduced pressure. The residue is taken up in 50 ml of diisopropyl ether. The precipitate formed is drained, washed twice with 5 ml of diisopropyl ether and then dried under reduced pressure. There is thus obtained 0.480 g (100%) of 3-benzyl-4,5-diphenyl-1-methylimidazolium bromide, in the form of a yellow solid, used as it is in the next step, whose characteristic is the following:

Workup

  1. customwhich was obtained
  2. temperatureAfter 2 days of heating
  3. temperatureunder reflux
  4. concentrationthe reaction medium is concentrated under reduced pressure
  5. customThe precipitate formed
  6. washwashed twice with 5 ml of diisopropyl ether
  7. customdried under reduced pressure

Sources & evidence

ORD record
ord-339b94affe63437897c82b92d8d5b3b4
Source dataset
uspto-grants-2015_03
Patent number
US08980875B2

Reaction notes

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