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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 874266Generated: October 31, 2026

O-(Tetrahydropyran-2-yl)hydroxylamine → HCID 87258321, compound

https://huagongshe.com/reaction/874266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-(Tetrahydropyran-2-yl)hydroxylamineHCID 5142091—
ReactantHCID 67071420HCID 67071420—
ProductHCID 87258321HCID 87258321—

Reaction Steps

(±)-(E)-3-[1′-Benzyl-4-oxo-spiro(chromane-2,4′-azepane)-6-yl]-acrylic acid (490 mg, 1.15 mmol) was reacted with NH2OTHP following the procedure described in Example 22, Step C, giving (E)-3-[1′-benzyl-4-oxo-spiro(chromane-2,4′-azepane)-6-yl]-N-(tetrahydro-pyran-2-yloxy)-acrylamide (270 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08980877B2
Source datasetuspto-grants-2015_03
ORD IDord-a176bb430ead4715bd194a3135b9a8e4
Source noteuspto-grants-2015_03