HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-(Tetrahydropyran-2-yl)hydroxylamine → HCID 87258291, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-(Tetrahydropyran-2-yl)hydroxylamine | HCID 5142091 | — |
| Reactant | HCID 67071726 | HCID 67071726 | — |
| Product | HCID 87258291 | HCID 87258291 | — |
Reaction Steps
(±)-(E)-3-[1′-Methyl-4-oxo-spiro(chromane-2,4′-azepane)-6-yl]-acrylic acid (330 mg, 0.94 mmol) was treated with NH2OTHP according to the procedure described in Example 23, Step C, giving (±)-(E)-3-[1′-methyl-4-oxo-spiro(chromane-2,4′-azepane)-6-yl]-N-(tetrahydro-pyran-2-yloxy)-acrylamide as a yellow solid (220 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08980877B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d3d291dd6b5a44b9a6bd2f0a42ef7668 |
| Source note | uspto-grants-2015_03 |