反应详情

N-benzyl-4-(3-chloro-4-methoxybenzyloxy)-2-(methylmercapto)pyrimidine-5-carboxamide (100 mg, 0.23 mmol) was dissolved in 10 mL of dichloromethane, m-CPBA (m-chloroperbenzoic acid, 40 mg, 0.23 mmol) was added and reacted at room temperature for 3 h, washed with water after the reaction is complete, extracted with dichloromethane, the organic layer was dried and dried by rotation to obtain yellow solid, and this product was directly used in the next reaction without purification.

1. customreacted at room temperature for 3 h
2. washwashed with water after the reaction
3. extractionextracted with dichloromethane
4. customthe organic layer was dried
5. customdried by rotation
6. customto obtain yellow solid
7. customthis product was directly used in the next reaction without purification