HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 7-bromoheptanoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 7-Bromoheptanoic acid | HCID 121723 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 7-bromoheptanoyl Chloride | HCID 11368152 | 100% |
Reaction Steps
to a suspension of 7-bromoheptanoic acid (1.7 g, 8.13 mmol) obtained above in CH2Cl2 (30 mL) were added oxalylchloride (2.13 mL, 24.39 mmol) and a catalytic amount of DMF. The mixture was stirred overnight at room temperature. The solvent was removed by evaporation in vacuo to give 1.84 g (100%) of the 7-bromoheptanoyl chloride as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08980909B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-fe3fa9c5d0fb40bb911a201ab89334cf |
| Source note | uspto-grants-2015_03 |