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HRID874593

反应详情

EQUATION

反应方程式

HRID 874593 的结构方程式

REACTANTS

反应物

3
结构：Cc1cc(COc2ccc(S(=O)(=O)Cl)cc2)c2ccccc2n1.Cl
HCID86607865

未命名化合物

结构：COC(=O)[C@H](CN)N1CCN(S(=O)(=O)CC(C)C)CC1.Cl.Cl
HCID86715684

未命名化合物

结构：COC(=O)[C@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N1CCN(S(=O)(=O)CC(C)C)CC1
HCID86715687

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N1CCN(S(=O)(=O)C=C(C)C)CC1
HCID86715686

未命名化合物

PROCEDURE

实验过程

In a manner analogous to example 3.6, using 621 mg (1.6 mmol) of methyl (S)-3-amino-2-[4-(2-methylpropane-1-sulfonyl)piperazin-1-yl]propanoate dihydrochloride and 876 mg (2.3 mmol) of 4-(2-methylquinolin-4-ylmethoxy)benzenesulfonyl chloride hydrochloride (prepared as described in example 17.2), 643 mg (64%) of methyl (S)-2-[4-(2-methylpropane-1-sulfonyl)piperazin-1-yl]-3-[4-(2-methylquinolin-4-ylmethoxy)benzenesulfonylamino]propanoate are obtained in the form of an oil.

WORKUP

后处理

  1. customare obtained in the form of an oil