1,4-Dioxane hydrochloride → 3-(1,3-Dioxolan-2-yl)propyl piperidine-4-carboxylate hydrochloride

Participants

Reaction Steps

HCl-dioxane (4 M, 5 mL, 20 mmol) was added to 4-(3-(1,3-dioxolan-2-yl)propyl) 1-tert-butyl piperidine-1,4-dicarboxylate (0.71 g, 2.07 mmol) and the reaction mixture was stirred at RT for 1.5 hours. The solvent was evaporated at reduced pressure. The crude material was used directly without purification.

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