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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 874997Generated: October 30, 2026

Trifluoroacetate → 5-(4-Fluorophenyl)-2-(piperidin-3-yl)oxazole TFA Salt

https://huagongshe.com/reaction/874997

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetateHCID 84468—
ReactantTert-butyl 3-(5-(4-fluorophenyl)oxazol-2-yl)piperidine-1-carboxylateHCID 69935244—
Product5-(4-Fluorophenyl)-2-(piperidin-3-yl)oxazole TFA SaltHCID 86673536—

Reaction Steps

This compound was synthesized from tert-butyl 3-(5-(4-fluorophenyl)oxazol-2-yl)piperidine-1-carboxylate as described for example 46 step 4 (150 mg, crude) as a trifluoroacetate salt and it was carried through without further purification. MS (ESI) m/z: Calculated for C14H16FN2O: 246.12. found: 247.0 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981084B2
Source datasetuspto-grants-2015_03
ORD IDord-b697462415b94b6082789b265a497d04
Source noteuspto-grants-2015_03