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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 875006Generated: October 29, 2026

Trifluoroacetate → 4-Phenyl-2-(piperazin-1-yl)pyrimidine TFA Salt

https://huagongshe.com/reaction/875006

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetateHCID 84468—
ReactantTert-butyl 4-(4-phenylpyrimidin-2-yl)piperazine-1-carboxylateHCID 68577436—
Product4-Phenyl-2-(piperazin-1-yl)pyrimidine TFA SaltHCID 86673538—

Reaction Steps

This compound was synthesized from tert-butyl 4-(4-phenylpyrimidin-2-yl)piperazine-1-carboxylate as described for example 46 step 4 (400 mg, crude) as a trifluoroacetate salt and it was carried through without further purification. MS (ESI) m/z: Calculated for C14H16N4: 240.14. found: 241.0 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981084B2
Source datasetuspto-grants-2015_03
ORD IDord-56d8047ab4b14301a56c14c124696faa
Source noteuspto-grants-2015_03