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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 875009Generated: October 29, 2026

1-(2-Fluorophenyl)piperazine → HCID 53327905, compound

https://huagongshe.com/reaction/875009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Fluorophenyl)piperazineHCID 70529—
Reactant3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acidHCID 25180854—
ProductHCID 53327905HCID 5332790528%

Reaction Steps

This compound was synthesized from 1-(2-fluorophenyl)piperazine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (45 mg, yield 28%). 1H NMR (400 MHz, CDCl3) δ 8.21-8.20 (m, 2H), 7.68-7.60 (m, 2H), 7.11-6.94 (m, 4H), 4.01 (m, 2H), 3.63 (m, 2H), 3.20-3.06 (m, 4H). MS (ESI) m/z: Calculated for C20H16F4N4O2: 420.12. found: 421.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981084B2
Source datasetuspto-grants-2015_03
ORD IDord-dc07f1d0bf1540b486a029724418548e
Source noteuspto-grants-2015_03