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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 875010Generated: October 29, 2026

1-(2-Methoxyphenyl)piperazine → HCID 53327906, compound

https://huagongshe.com/reaction/875010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methoxyphenyl)piperazineHCID 1346—
Reactant3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acidHCID 25180854—
ProductHCID 53327906HCID 5332790628%

Reaction Steps

This compound was synthesized from 1-(2-methoxy-phenyl)-piperazine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (63 mg, yield 28%). 1H NMR (400 MHz, CDCl3) δ 8.22-8.19 (m, 2H), 7.69-7.60 (m, 2H), 7.08-7.04 (m, 1H), 6.96-6.89 (m, 3H), 4.02 (m, 2H), 3.89 (s, 3H), 3.64 (m, 2H), 3.18 (m, 2H), 3.04 (m, 2H). MS (ESI) m/z: Calculated for C21H19F3N4O3: 432.14. found: 433.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981084B2
Source datasetuspto-grants-2015_03
ORD IDord-7b4fca0d14934c56a06220902fb55a39
Source noteuspto-grants-2015_03