Pyrrolidine → 3-[1-(6-Ethoxy-2-morpholino-7-pyrrolidinylcarbonylmethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-1,6-dimethyl-2,4-dioxoquinazoline
Reaction equation
[C:1](=[O:2])([OH:3])[CH2:4][O:5][c:6]1[c:7]([O:42][CH2:43][CH3:44])[cH:8][c:9]2[c:10]([N:22]3[CH2:23][CH2:24][CH:25]([n:28]4[c:29](=[O:41])[n:30]([CH3:40])[c:31]5[cH:32][cH:33][c:34]([CH3:39])[cH:35][c:36]5[c:37]4=[O:38])[CH2:26][CH2:27]3)[n:11][c:12]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[n:13][c:14]2[cH:15]1.[CH2:45]1[CH2:46][CH2:47][NH:48][CH2:49]1>>[C:1](=[O:2])([CH2:4][O:5][c:6]1[c:7]([O:42][CH2:43][CH3:44])[cH:8][c:9]2[c:10]([N:22]3[CH2:23][CH2:24][CH:25]([n:28]4[c:29](=[O:41])[n:30]([CH3:40])[c:31]5[cH:32][cH:33][c:34]([CH3:39])[cH:35][c:36]5[c:37]4=[O:38])[CH2:26][CH2:27]3)[n:11][c:12]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[n:13][c:14]2[cH:15]1)[N:48]1[CH2:47][CH2:46][CH2:45][CH2:49]1Participants
3
Sources & evidence
- ORD record
- ord-2d6fef349cc14ce080fc2fb433099415
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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