HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 876163Generated: October 31, 2026
Hydrochloric Acid → HCID 86673658, compound
https://huagongshe.com/reaction/876163
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 86673658 | HCID 86673658 | 61% |
Reaction Steps
250 mg of 4,6-dichloropyrimidine and 165 mg of m-chloroaniline were dissolved in 2.5 mL of i-PrOH and 0.25 mL of 37% HCl were added. The mixture obtained was refluxed (84° C.) for 2.5 hours under nitrogen atmosphere. A colorless precipitate was formed which was collected by filtration. 6-Chloro-N-(3-chlorophenyl)pyrimidin-4-amine hydrochloride in the form of colorless crystals was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08986994B2 |
|---|
| Source dataset | uspto-grants-2015_03 |
|---|
| ORD ID | ord-f5a7a0419ef84682836d9750ac7b4b97 |
|---|
| Source note | uspto-grants-2015_03 |
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